ABSTRACT

Our planet earth has seen many  viral pandemics The most recent pandemic was Severe Acute Respiratory Syndrome (SARS-CoV-2) commonly called Corona Virus disease (COVID-19). It was first reported  inWuhan Peoples Republic of China, in December 2019. COVID-19 is a positive-sense single-strand enveloped RNA virus mainly found in mammals. To date, a total of six species of coronavirus have been reported that affected humans. These mainly cause respiratory, hepatic, enteric, and neurological complications. Since it is a novel virus, different therapies were used for the treatment These measures comprised of mostly repurposing of already available drugs, more specifically antiviral drugs. In this review article, we have summarized the virus-host relation and chemical structure and also discussed in detail the proposed mechanism of these repurposed antivirals drugs.

Key Words: Covid-19, Cytokin Storm, Therapeutic Drugs, Virus.

How to cite this: Haider A, Faheem M, Jamal SB, Naeem M, Khalil AAK, Khan R, Subhan F. Repurposing of Antiviral Drugs for treatment of COVID19 Infection: A Mini-Review. Life and Science. 2020; 1(suppl): 32-37.  doi: http://doi.org/10.37185/LnS.1.1.155