ABSTRACT

Objective: This study aimed to evaluate retinal nerve fiber layer (RNFL) thickness in healthy individuals with myopic and hypermetropic eyes, using optical coherence tomography (OCT).
Study Design: A cross-sectional study.
Place and Duration of the Study: The study was carried out at the Department of Ophthalmology, Dr. Akil bin Abdul Qadir Institute of Ophthalmology, Karachi, Pakistan from January 2015 to June 2015.
Methods: In this study, 300 eyes were included were examined using standard protocols by a single examiner. Subjects with a history of diabetic or hypertensive retinopathy, raised intraocular pressure (> 21mmHg), and previous intraocular or laser surgery were excluded from the study. The mean retinal nerve fiber layer thickness was calculated in both myopic and hypermetropic eyes.
Results: The mean global retinal nerve fiber layer thickness (RNFLT) in myopic eyes was found to be 93.98 ± 8.57 μm. In hypermetropic eyes, it was found to be 101.00 ± 6.58. This variation was found to be statistically significant with p-value of 0.001.
Conclusion: We concluded that individuals with myopic eyes had significantly reduced retinal nerve fiber layer thickness whereas those with hypermetropic eyes showed an insignificant increase in RNFLT compared to emmetropic eyes.

Keywords: Hypermetropia, Myopia, Optical Coherence Tomography, Retina.

How to cite this: Mukhtar S, Hassan N, Lakhani M, Fatima U, Shaheen S, Raza I. Retinal Nerve Fiber Layer Thickness (RNFLT) in Myopic & Hypermetropic Eyes in a Subset of Pakistani Population. Life and Science. 2024; 5(1): 54-60   . doi: