1- Adherence to the ARRIVE guidelines is achieved through transparent reporting of study design, experimental units, and methodologies. For more detailed guidance, refer to the official ARRIVE guidelines website: https://arriveguidelines.org/. https://arriveguidelines.org/arrive-guidelines

2- To support transparency and reproducibility, authors must include a statement in the manuscript explicitly confirming that the study was conducted and reported by the ARRIVE guidelines (version 2.0). Please complete the ARRIVE 2.0 Author Checklist and submit it as a supplementary file. The checklist is designed to help authors ensure that all critical elements are reported and to assist the editorial team in assessing compliance. The editorial team will consider all manuscripts reporting animal research using the ARRIVE Essential 10 as a benchmark for quality and transparency.