Increased Frequency of Dermatological Diseases in Parkinson's Patients

Abstract

Objective: To determine the frequency of seborrheic dermatitis, bullous pemphigoid, rosacea, and melanoma
among the patients diagnosed with Parkinson Disease.
Study Design: Cross sectional study.
Place and Duration of Study: The study was carried out at Dermatology Department of Bakhtawar Amin Trust
th th Teaching Hospital Multan from 13 May to 13 October 2020.
Materials and Methods: A total of 80 patients of Parkinson disease were evaluated for skin disorders. Disease
severity was confirmed through Hoehn Yahr staging criteria (H-Y stage). Skin characteristics and disease
diagnosis was made through finding sebum production levels, hot/cold flush test, immunofluorescence and
biopsy evaluation for seborrheic dermatitis, rosacea, bullous pemphigoid, and melanoma, respectively. The
test results were compared with control subject. Chi square test and student t-test were used to find the
significance of results. P < 0.05 will be statistically significant.
Results: Out of 80, 44 patients were positive for skin disorders. The frequency of seborrheic dermatitis was
31.2% and was quite high as compared to control group that was 25% whereas rosacea, bullous pemphigoid
and melanoma was found in 15%, 6.2% and 2.5% patients and in control group they were 11.2%, 2.5% and 1.0%
respectively. To detect the significant difference between quantitative variables of test and control group, chi
square was used and student t-test was used to compare the qualitative variables. P < 0.05 will be statistically
significant.
Conclusion: Skin disorders are highly prevalent among Parkinson's patients than control population.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited