Applications of Nanoparticles in Treatment of Respiratory Disorders

Abstract

Respiratory disorders are very prevalent and high-incidence group of diseases having severe impacts on human
health in the world. Some of the respiratory disorders are difficult to diagnose and treat, such as chronic
obstructive pulmonary disease, asthma, lungs cancer, and pulmonary tuberculosis. Lungs cancer is the second
most common cancer globally. Nano-delivery technologies have a great potential to improve the drug targeting
in a specific area of infections in respiratory disease treatment. Not only nanoparticles concentrate the drug at
specific-disease sites but also reduce the drug degradation and drug loss simultaneously. Sedimentation,
nebulizers, carbon nanodots, and stimulus-responsive nanoparticles are currently being explored to use as a
source for delivering nanodrugs to treat lungs cancer. Various nanoparticles such as steroids, salbutamol,
liposome-mediated, and polystyrene are used in the treatment of asthma and preterm birth diseases. This
study focused on different kinds of nanoparticles like gold, solid lipid nanoparticles (NPs), steroidal and
liposome-mediated nanoparticles which are used to treat different pulmonary or respiratory disorders and also
examine the current therapeutic techniques for the diagnosis of lung diseases and therapy using nanoscalebased
inhalers.